How to Use kinase in a Sentence

kinase

noun
Definition of kinasenext
  • That signal involves the production of a type of cytokine called a Janus kinase, or JAK.
    — Marla Broadfoot, Scientific American, 1 Sep. 2021
  • Tanzi and his colleagues blocked a variety of different enzymes called kinases to try to stop the process.
    — Karen Weintraub, Scientific American, 16 Jan. 2020
  • The drug belongs to a large class of cancer drugs called tyrosine kinase inhibitors, the fruits of research by Tony Hunter at the Salk Institute four decades ago.
    — San Diego Union-Tribune, 17 Sep. 2019
  • The virus most powerfully hijacks a kinase called CK2, which plays a key role in the basic frame of the cell as well as its growth, proliferation and death.
    — Mark Johnson, Milwaukee Journal Sentinel, 27 June 2020
  • The tests also look for whether the blood increases CaM kinase II activity.
    — Pamela Weintraub, Discover Magazine, 3 Jan. 2019
  • Among them was a compound called silmitasertib, which inhibits a kinase called CK2, and is being tested as a cancer drug.
    — Gregory Barber, Wired, 27 June 2020
  • The tests were performed by virologists at Mount Sinai and the Institut Pasteur, who infected host cells with the virus and added the kinase inhibitors.
    — Jason Fagone, SFChronicle.com, 26 June 2020
  • In more severe cases, some patients may use Janus kinase inhibitors.
    — NBC News, 7 Jan. 2022
  • Zelboraf targets patients who test positive for a variant of the BRAF gene, another kinase that can go haywire and cause cells to grow out of control.
    — David Ewing Duncan, Discover Magazine, 30 Oct. 2012
  • One street that seemed particularly active was ruled by a kinase called Casein Kinase II, which happened to be one of the 332 proteins flagged in the team’s earlier protein map.
    — Jason Fagone, SFChronicle.com, 26 June 2020
  • ArQule, based in Woburn, Mass., is focused on kinase inhibitor discovery.
    — Washington Post, 9 Dec. 2019
  • The startup is developing drugs that rely on enzyme blockers known as kinase inhibitors to keep cancer cells from growing.
    — BostonGlobe.com, 29 July 2021
  • Finally, Krogan and his colleagues found that the virus also hijack a kinase that helps cells stay healthy in different environments and cleans out damaged cells.
    — Mark Johnson, Milwaukee Journal Sentinel, 27 June 2020
  • The startup is developing lung cancer drugs that rely on enzyme blockers known as kinase inhibitors to help keep cancer cells from growing.
    — BostonGlobe.com, 14 May 2021
  • One drug candidate emerged at the top of the pack: c-Jun N-terminal kinase inhibitor SU3327, which is already being studied as a possible treatment for diabetes.
    — Quanta Magazine, 9 Mar. 2020
  • Spectrum of discovery The Nature study can be viewed as an extension of Hunter’s groundbreaking work in tyrosine kinases.
    — Bradley J. Fikes, sandiegouniontribune.com, 4 Apr. 2018
  • Drugs called kinase inhibitors work by changing cellular function to fight itchiness.
    — Dr. Marty Becker and Kim Campbell Thornton, sacbee.com, 28 Apr. 2017
  • Pyrukynd is a pill for a hereditary blood disorder called pyruvate kinase deficiency.
    — Globe Staff, BostonGlobe.com, 12 July 2022
  • For his part, Hunter performed research that led to an entirely new category of cancer drugs called tyrosine kinase inhibitors.
    — San Diego Union-Tribune, 19 Aug. 2019
  • Hunter made his reputation with the 1979 discovery of how enzymes called tyrosine kinases can cause cancer.
    — Bradley J. Fikes, sandiegouniontribune.com, 4 Apr. 2018
  • Given as a pill, mitapivat is designed to activate an enzyme called pyruvate kinase-R that red blood cells use to convert sugars into energy.
    — Adam Feuerstein, STAT, 18 Feb. 2022
  • Such tyrosine kinase inhibitors constitute a large class of cancer drugs, made possible by the research of Salk Institute scientist Tony Hunter.
    — Bradley J. Fikes, sandiegouniontribune.com, 4 Sep. 2017
  • Most recently, autoimmune drugs known as Janus kinase inhibitors -- JAK inhibitors -- have been found to produce a full head of hair in patients with moderate to severe alopecia areata, a type of baldness that affects both men and women.
    — Susan Scutti, CNN, 9 May 2018
  • In 1998 Druker started a clinical trial with his tyrosine kinase inhibitor.
    — Tony Dajer, Discover Magazine, 7 Feb. 2010
  • These proteins, called receptor-like kinases, or RLKs, contain a sensory area outside the cell membrane that attaches to molecules in the environment.
    — Lakshmi Sandhana, WIRED, 5 Apr. 2003
  • Choanoflagellates have genes for tyrosine kinases, enzymes that, in complex animals, help control the functions of specialized cells, such as insulin secretion in the pancreas.
    — Elizabeth Pennisi, Science | AAAS, 28 June 2018
  • Both monoclonal antibodies and tyrosine kinases now provide the basis for many new medicines coming to market.
    — Fred D. Ledley, STAT, 6 June 2018
  • The class of cancer drugs that block phosphorylation activity are called tyrosine kinase inhibitors.
    — Bradley J. Fikes, sandiegouniontribune.com, 4 Apr. 2018
  • Other cancer therapies, such as a class of drugs known as Bruton's tyrosine kinase inhibitors, may be protective and are being tested in coronavirus patients without cancer.
    — Emily Woodruff, NOLA.com, 6 Aug. 2020
  • Dumbfounded but also aware that my own primary care doctor is vigilant about my A1c level (a measure of diabetes) and an enzyme calledcreatine kinase (a sign of heart disease) but never asks about my mental health.
    — Steven Petrow, chicagotribune.com, 23 Sep. 2019

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'kinase.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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