protease inhibitor

noun

: a substance that inhibits the action of a protease
specifically : any of various drugs (such as indinavir) that inhibit the action of the protease of HIV so that the cleavage of viral proteins into mature functional infectious particles is prevented and that are used especially in combination with other agents in the treatment of HIV infection

Examples of protease inhibitor in a Sentence

Recent Examples on the Web Later that year, the F.D.A. evaluated a new protease inhibitor that was still in early-stage trials. Gideon Lewis-Kraus, The New Yorker, 19 June 2023 The gene’s technical name, epididymal protease inhibitor, is usually shortened to the friendlier EPPIN. Gabe Allen, Discover Magazine, 9 Feb. 2022 In 1999, a French study first confirmed that hair loss was a side effect of men using the protease inhibitor Crixivan (indinavir). Emily Rekstis, Allure, 26 Oct. 2022 Paxlovid combines nirmatrelvir, an inhibitor of the SARS-CoV-2 main protease (MPro, also known as 3CL or nsp5), and ritonavir, an HIV-1 protease inhibitor and CYP3A inhibitor. William A. Haseltine, Forbes, 9 June 2022 See all Example Sentences for protease inhibitor 

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'protease inhibitor.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1943, in the meaning defined above

Time Traveler
The first known use of protease inhibitor was in 1943

Dictionary Entries Near protease inhibitor

Cite this Entry

“Protease inhibitor.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/protease%20inhibitor. Accessed 18 Aug. 2024.

Medical Definition

protease inhibitor

noun
: a substance that inhibits the action of a protease
specifically : any of various drugs (as indinavir or saquinavir) that inhibit the action of HIV protease so that cleavage of viral proteins into mature infectious particles is prevented and that are used especially in combination with other antiretroviral agents in the treatment of HIV infection

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