genetic mutation

noun

plural genetic mutations
: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes
Lacking working copies of the p53 gene, cells can begin to divide without check, though several other genetic mutations are thought to be needed to foster a full-blown malignancy.Natalie Angier

Examples of genetic mutation in a Sentence

Recent Examples on the Web In fact, the most common type of hemochromatosis is hereditary hemochromatosis, which occurs due to a genetic mutation. Sarah Jividen, Health, 12 Sep. 2024 Interestingly and maybe worryingly, while most genetic mutations have no effect at all, some can cause viruses to become deadlier or more effective at spreading. Jess Craig, Vox, 15 Aug. 2024 It’s caused by a genetic mutation that affects the way cholesterol is cleared by the body, prompting it to build up in and ultimately clog your arteries and veins. Angela Haupt, TIME, 12 Aug. 2024 This problem is congenital (present at birth) and linked to several genetic mutations. Anna Giorgi, Verywell Health, 8 Aug. 2024 See all Example Sentences for genetic mutation 

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'genetic mutation.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1915, in the meaning defined above

Time Traveler
The first known use of genetic mutation was in 1915

Dictionary Entries Near genetic mutation

Cite this Entry

“Genetic mutation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genetic%20mutation. Accessed 17 Sep. 2024.

Medical Definition

genetic mutation

noun
: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes
Gaucher's disease results from one of many genetic mutations that can either slow or prevent the breakdown of certain glycolipids, which accumulate in storage vesicles and eventually kill cells.Joseph Alper
Last Updated: - Updated example sentences
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