Down syndrome

noun

variants or Down's syndrome
: a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in cognitive functioning, short stature, upward slanting eyes, a flattened nasal bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21

called also trisomy 21

Examples of Down syndrome in a Sentence

Recent Examples on the Web Neanderthal community cared for child with Down syndrome, fossil suggests Bone found in Spain provides evidence of collaboration, compassion. Naomi Nix, Washington Post, 30 June 2024 According to the study, life expectancy in 1929 for children with Down syndrome, a condition caused by an extra partial or full chromosome, was 9 years. Katie Hunt, CNN, 27 June 2024 Some other researchers aren’t convinced the evidence is strong enough to say for sure that the child had Down syndrome. Will Sullivan, Smithsonian Magazine, 27 June 2024 Beauty, which counts Paralympic swimmer Anastasia Pagonis as an ambassador, and Gucci, which tapped Ellie Goldstein, a model with Down syndrome, are among those making strides in meaningful representation. Noor Lobad, WWD, 27 June 2024 See all Example Sentences for Down syndrome 

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'Down syndrome.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

J. L. H. Down †1896 English physician

First Known Use

1961, in the meaning defined above

Time Traveler
The first known use of Down syndrome was in 1961

Dictionary Entries Near Down syndrome

Cite this Entry

“Down syndrome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/Down%20syndrome. Accessed 15 Jul. 2024.

Kids Definition

Down syndrome

noun
ˈdau̇n-
variants or Down's syndrome
ˈdau̇n(z)-
: a genetic condition characterized especially by developmental delays, by distinctive physical traits (as short stature and upward slanting eyes), and by the presence of three chromosomes numbered 21 in human beings
Etymology

named for J.L.H. Down, 1828–1896, English doctor

Medical Definition

Down syndrome

noun
variants or Down's syndrome
: a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in cognitive functioning, short stature, relatively small head, upward slanting eyes usually with epicanthal folds, flattened nasal bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21

called also Down, Down's, trisomy 21

More from Merriam-Webster on Down syndrome

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