blood-brain barrier

noun

: a naturally occurring barrier created by the modification of brain capillaries (as by reduction in fenestration and formation of tight cell-to-cell contacts) that prevents many substances from leaving the blood and crossing the capillary walls into the brain tissues

Examples of blood-brain barrier in a Sentence

Recent Examples on the Web Unlike most pathogens, Toxoplasma can cross the blood-brain barrier and invade brain cells. Bill Sullivan, Discover Magazine, 12 Aug. 2024 This can cause the blood-brain barrier, a network of tissue and vessels that prevents harmful substances from reaching your brain, to become compromised, causing catastrophic consequences. Elizabeth B. Kim, The Enquirer, 17 Aug. 2024 All drugs, especially biologics, have great difficulty penetrating the brain due to the blood-brain barrier. Bill Sullivan, Discover Magazine, 12 Aug. 2024 Scientists have discovered how to use the parasite’s ability to cross the blood-brain barrier to deliver a therapy for Rett syndrome, a neurodevelopmental disorder that causes severe symptoms, including seizures, loss of speech, loss of muscle tone, and difficulty breathing. Avery Hurt, Discover Magazine, 6 Aug. 2024 See all Example Sentences for blood-brain barrier 

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'blood-brain barrier.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1934, in the meaning defined above

Time Traveler
The first known use of blood-brain barrier was in 1934

Dictionary Entries Near blood-brain barrier

Cite this Entry

“Blood-brain barrier.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/blood-brain%20barrier. Accessed 12 Sep. 2024.

Medical Definition

blood-brain barrier

noun
: a naturally occurring barrier created by the modification of brain capillaries (as by reduction in fenestration and formation of tight cell-to-cell contacts) that prevents many substances from leaving the blood and crossing the capillary walls into the brain tissues
abbreviation BBB

More from Merriam-Webster on blood-brain barrier

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