antigen

noun

an·​ti·​gen ˈan-ti-jən How to pronounce antigen (audio)
-ˌjen
: any substance (such as an immunogen or a hapten) foreign to the body that evokes an immune response either alone or after forming a complex with a larger molecule (such as a protein) and that is capable of binding with a product (such as an antibody or T cell) of the immune response
antigenic adjective
antigenically adverb
antigenicity noun

Did you know?

An antibody is a protein produced by your immune system to fight outside invaders. Since the enemy substance actually triggers the production of antibodies, such substances are called antigens—anti- being short for antibody, and -gen meaning "producer". (In a similar way, an allergen produces an allergy, and a pathogen produces a pathology or disease.) Antigens are often rodlike structures that stick out from the surface of an invading organism—usually a bacterium or a virus—and allow it to attach itself to cells in the invaded body. But unfortunately for them, in doing so they let the immune system know they're present, and the body is flooded with an army of Pac-Man-like antibodies.

Examples of antigen in a Sentence

Recent Examples on the Web Rapid tests—which work by detecting proteins known as antigens from the virus that causes COVID-19—can’t specify which variant a person has; they’ve been designed to detect all variants. Maggie O'Neill, Verywell Health, 21 June 2024 These drugs were designed to bind a receptor protein found on the surface of prostate cancer cells, known as prostate-specific membrane antigen (PSMA). Elie Dolgin, Ars Technica, 21 June 2024 The macrophage eats the virus, creating antigens that kick-start T-cells, which then activate B-cells to help white blood cells attack the cold virus. Vulture Editors, Vulture, 11 June 2024 In addition to the major blood types, there are hundreds of antigens for red blood cells, some of which are unique to racial and ethnic groups. Ken Alltucker, USA TODAY, 9 Jan. 2024 See all Example Sentences for antigen 

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'antigen.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

German, from French antigène, from anticorps antibody + -gène -gen

First Known Use

1908, in the meaning defined above

Time Traveler
The first known use of antigen was in 1908

Dictionary Entries Near antigen

Cite this Entry

“Antigen.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antigen. Accessed 15 Jul. 2024.

Kids Definition

antigen

noun
an·​ti·​gen ˈant-i-jən How to pronounce antigen (audio)
-ˌjen
: a substance (as a protein) that causes the body to form antibodies against it when it is introduced into the body either alone or as part of a microscopic plant or animal
antigenic adjective

Medical Definition

antigen

noun
an·​ti·​gen ˈant-i-jən How to pronounce antigen (audio)
: any substance (as an immunogen or a hapten) foreign to the body that evokes an immune response either alone or after forming a complex with a larger molecule (as a protein) and that is capable of binding with a product (as an antibody or T cell) of the immune response
antigenic adjective
antigenically adverb

More from Merriam-Webster on antigen

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